Follow the on-screen guides to locate the two parts needed for the organ.
Insert both parts into the organ, then protect it as it powers on and activates Pack-a-Punch.
Kill O.S.C.A.R using three different traps around the map. Complete all three in any order. After the third trap, O.S.C.A.R will drop the wonder weapon.
Telescope
Shoot a blinking lamppost somewhere on the map to collect the wires. Then find a valve spitting steam and shoot five in a row to power on the telescope. Align the telescope with the sun — a laser will project onto the screen. Kill O.S.C.A.R in the trap.
Tesla Coil
Shoot the trunk of Ol' Tessie with a packed weapon — a car battery will shoot out of the hood. Take the battery to the trap in the Luminarium. Starting the trap with O.S.C.A.R nearby triggers a lockdown to drain his power.
Rocketship
Using Cryo Freeze, shoot the purple aether crystals around the map. Once you have three, kill Klaus with the rocket engine near Speed Cola.
Follow O.S.C.A.R as he patrols the map — he will begin playing audio logs. When he reaches Execution Twenty, Thurston will begin saying planet names.
Listen closely and translate the planet names into numbers using the key below, then insert the three-digit code into the box in the PAP room.
An elevator will drop down containing a Cryo Key.
Take the Cryo Key to the cryogenic chamber in the bar area.
Grab a saw from a case in the museum and use it to saw the brain out of Thurston.
Take the brain to the container near Juggernog and swap the brains, triggering a lockdown.
After the lockdown, take the new brain downstairs by the library and place it.
Once the brain is placed, pay attention to Thurston's reading list that flashes on the screen. The book names will be found in the library.
There are three busts in the library. Count how many books are near each bust — you can turn each head up to two times, matching the number of books closest to it.
Once all three are turned correctly, a door will open up the ladder. Climb the ladder and grab the Neptune planet.
Go to the telescope in the PAP room and find the coordinates for Mars. Insert those numbers into the device above the brain to open it.
Place the Neptune planet on the missing planet slot.
Find the three papers around the map showing where to place the three movable planets.
Move the planets to their correct spots, then interact with the brain to trigger another lockdown. An O.S.C.A.R will spawn — destroy the drones as the portal stabilizes.
Place the brain in the main contraption and interact with it to trigger a noise.
Look outside the map and shoot four towers from farthest to closest to attract a scarab beetle. Then hit the middle tower above the portal.
When able, jump to collect the beetle and place it in the device at the back corner of Mars.
Take the wonder weapon and shoot the metal prongs coming out of the pillars.
Return to the organ, interact with it, and memorize the order of symbols that appear.
Interact with the same symbols on the pillars in Mars in the same order they appeared on the organ.
Interact with the brain to start the boss fight.
I
Soul Boxes
Fill up soul boxes three times, then interact with the brain to shoot the boss in the sky.
II
Crit Phase
Spam her with the wonder weapon until crit spots open up, then spam those with your secondary.
III
Crit Phase
Repeat — wonder weapon to open crit spots, secondary weapon to damage them.
IV
Final Phase
Same pattern — keep pressure on her with the wonder weapon and secondary until the fight ends.